MyBioSource.com's DCC Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Immunofluorescence. The DCC Antibody was generated using DCC, and Netrin receptor DCC as the antigen and it reacts with Human.
Description
Receptor for netrin required for axon guidance. Mediates axon attraction of neuronal growth cones in the developing nervous system upon ligand binding. Its association with UNC5 proteins may trigger signaling for axon repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand. Implicated as a tumor suppressor gene.Hedrick L., Genes Dev. 8:1174-1183(1994).Cho K.R., Genomics 19:525-531(1994).Sjoeblom T., Science 314:268-274(2006)